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Generally, therapy can be diminished by twenty five% to 50% on a daily basis with careful checking for signals and indications of withdrawal (see Drug Abuse And Dependence for description with the symptoms and indicators of withdrawal). When the affected individual develops these indications or signs and symptoms, the dose should be raised to your past level and titrated down far more gradually, both by escalating the interval concerning decreases, decreasing the amount of alter in check here dose, or both equally.
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